{"id":1507,"date":"2018-04-16T08:11:45","date_gmt":"2018-04-16T07:11:45","guid":{"rendered":"http:\/\/www.khfi.de\/?page_id=1507"},"modified":"2019-07-10T11:05:05","modified_gmt":"2019-07-10T10:05:05","slug":"strukturelle-kardiologie","status":"publish","type":"page","link":"https:\/\/www.khfi.de\/khfiweb\/?page_id=1507","title":{"rendered":"Arbeitsgruppe Strukturelle Kardiologie"},"content":{"rendered":"

\"\"Die Arbeitsgruppe strukturelle\u00a0 Kardiologie besch\u00e4ftigt sich mit der interventionellen Therapie struktureller Herzerkrankungen. Klinisch werden in diesem Zusammenhang alle M\u00f6glichkeiten der interventionellen Klappentherapie inkl. z.b. Transkatheter-Aortenklappenimplantationen, Mitra-Clip, Mitralklappenvalvuloplastie sowie Cardioband in interdisziplin\u00e4rer Zusammenarbeit mit der Kardiochirurgie durchgef\u00fchrt. Die Kerckhoff-Klinik geh\u00f6rt zu einem der gr\u00f6\u00dften Zentren der interventionellen Klappentherapie in Deutschland, sie ist Schulungszentrum f\u00fcr nationale und internationale G\u00e4ste. Weiterhin werden die transkoronare Ablation der septalen Hypertrophie bei Patienten mit hypertroph-obstruktiver Kardiomyopathie (TASH), die Implantation von linksventrikul\u00e4ren Partitionierungsdevices (Parachute), LAA Okkluder sowie der Verschluss von persistierendem Foramen ovale, ASD und VSD durchgef\u00fchrt.<\/p>\n

Insbesondere f\u00fcr \u00e4ltere Patienten mit hohem bis sehr hohem operativen Risiko stellen Methoden wie die\u00a0Transkatheter Aortenklappenimplantationen (TAVI) die Therapie der Wahl bei symptomatischer Aortenklappenstenose dar. Zum gro\u00dfen Erfolg dieser Methode haben nicht nur eine zunehmende Erfahrung, eine verbesserte Patientenselektion und Bildgebung, der Einsatz von neuen Technologien, sondern auch die interdisziplin\u00e4re Zusammenarbeit im Heart Team gef\u00fchrt. Die Kerckhoff-Klinik ist Referenzzentrum f\u00fcr verschiedene Klappensysteme (Symetis, Edwards, Portico). Regelhaft wird die Prozedur TAVI an unserem Standort wissenschaftlich begleitet z.B. in zentrumsspezifischen aber auch internationalen Studien.\u00a01<\/sup><\/span>,2<\/sup><\/span>,3<\/sup><\/span>,4<\/sup><\/span>,5<\/sup><\/span>,6<\/sup><\/span>,7<\/sup><\/span>,8<\/sup><\/span><\/p>\n

Beispielhaft genannt sei hier auch die klinisch relevante wissenschaftliche Evaluation ballon- und selbstexpandierbare Klappenprothesen hinsichtlich prozeduraler Ergebnisse und Mortalit\u00e4t miteinander zu vergleichen.9<\/sup><\/span>,10<\/sup><\/span>,11<\/sup><\/span>,12<\/sup><\/span><\/sup><\/p>\n

In den derzeitigen Leitlinien stellen bikuspide Aortenklappen eine relative Kontraindikation f\u00fcr eine TAVI dar. Die Datenlage sowohl zu Pr\u00e4valenz als auch zu klinischen Ergebnissen ist jedoch inkonsistent. Durch Nutzung modernen Bildgebungverfahren k\u00f6nnen bikuspide Aortenklappen erkannt und klassifiziert werden. Auch erfolgt eine wissenschaftliche Evaluation der Behandlungsergebnis einer TAVI bei Patienten mit bikuspider Aortenklappe.13<\/sup><\/span><\/sup><\/p>\n

<\/h5>\n
<\/h5>\n
Beteiligte Personen<\/h5>\n

Dr. W.-K. Kim
\nPD Dr. O. D\u00f6rr
\nProf. Dr. C. Liebetrau
\nPD Dr. U. Fischer-Rasokat
\nDr. M. Renker
\nDr. Marko Dahmer
\nDr. S. Keranov<\/p>\n

Aktuelle Publikationen<\/strong><\/h5>\n
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1.<\/div>\n
M\u00f6llmann H, Hengstenberg C, Hilker M, Kerber S, Sch\u00e4fer U, Rudolph T, Linke A, Franz N, Kuntze T, Nef H, Kappert U, Walther T, Zembala M, Toggweiler S, Kim W. Real-world experience using the ACURATE neo prosthesis: 30-day outcomes of 1,000 patients enrolled in the SAVI TF registry. EuroIntervention<\/i> 2018;13<\/b>:e1764\u2013e1770. [PubMed<\/a>]<\/span><\/div>\n<\/div>\n<\/div>\n
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2.<\/div>\n
Husser O, Fujita B, Hengstenberg C, Frerker C, Beckmann A, M\u00f6llmann H, Walther T, Bekeredjian R, B\u00f6hm M, Pellegrini C, Bleiziffer S, Lange R, Mohr F, Hamm C, Bauer T, Ensminger S, GARY E. Conscious Sedation Versus General\u00a0Anesthesia in Transcatheter\u00a0Aortic Valve\u00a0Replacement: The German Aortic Valve Registry. JACC Cardiovasc Interv<\/i> 2018;11<\/b>:567\u2013578. [PubMed<\/a>]<\/span><\/div>\n<\/div>\n<\/div>\n
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3.<\/div>\n
Gaede L, Blumenstein J, Liebetrau C, D\u00f6rr O, Kim W, Nef H, Husser O, Els\u00e4sser A, Hamm C, M\u00f6llmann H. Outcome after transvascular transcatheter aortic valve implantation in 2016. Eur Heart J<\/i> 2018;39<\/b>:667\u2013675. [PubMed<\/a>]<\/span><\/div>\n<\/div>\n<\/div>\n
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4.<\/div>\n
Arsalan M, Maren W, Hecker F, Filardo G, Kim W, Pollock B, Van L, Arsalan-Werner A, Renker M, Doss M, Kalbas S, Hamm C, Liebetrau C, Mack M, Walther T. TAVI risk scoring using established versus new scoring systems: role of the new STS\/ACC model. EuroIntervention<\/i> 2018;13<\/b>:1520\u20131526. [PubMed<\/a>]<\/span><\/div>\n<\/div>\n<\/div>\n
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5.<\/div>\n
Arsalan M, Kim W, Van L, Liebetrau C, Pollock B, Filardo G, Renker M, M\u00f6llmann H, Doss M, Fischer-Rasokat U, Skwara A, Hamm C, Walther T. Predictors and outcome of conversion to cardiac surgery during transcatheter aortic valve implantation. Eur J Cardiothorac Surg<\/i> 2018; [PubMed<\/a>]<\/span><\/div>\n<\/div>\n<\/div>\n
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6.<\/div>\n
M\u00f6llmann H, Walther T, Siqueira D, Diemert P, Treede H, Grube E, Nickenig G, Baldus S, Rudolph T, Kuratani T, Sawa Y, Kempfert J, Kim W, Abizaid A. Transfemoral TAVI using the self-expanding ACURATE neo prosthesis: one-year outcomes of the multicentre \u2018CE-approval cohort\u2019. EuroIntervention<\/i> 2017;13<\/b>:e1040\u2013e1046. [PubMed<\/a>]<\/span><\/div>\n<\/div>\n<\/div>\n
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7.<\/div>\n
Kim W, Hamm C. The Future of TAVI. Eur Heart J<\/i> 2017;38<\/b>:2704\u20132707. [PubMed<\/a>]<\/span><\/div>\n<\/div>\n<\/div>\n
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8.<\/div>\n
Gaede L, Kim W, Blumenstein J, Liebetrau C, D\u00f6rr O, Nef H, Hamm C, Walther T, Achenbach S, Els\u00e4sser A, M\u00f6llmann H. Temporal trends in transcatheter and surgical aortic valve replacement\u202f: An analysis of aortic valve replacements in\u00a0Germany during 2012-2014. Herz<\/i> 2017;42<\/b>:316\u2013324. [PubMed<\/a>]<\/span><\/div>\n<\/div>\n<\/div>\n
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9.<\/div>\n
Mauri V, Kim W, Abumayyaleh M, Walther T, Moellmann H, Schaefer U, Conradi L, Hengstenberg C, Hilker M, Wahlers T, Baldus S, Rudolph V, Madershahian N, Rudolph T. Short-Term Outcome and Hemodynamic Performance of Next-Generation Self-Expanding Versus Balloon-Expandable Transcatheter Aortic Valves in Patients With Small Aortic Annulus: A Multicenter Propensity-Matched Comparison. Circ Cardiovasc Interv<\/i> 2017;10<\/b>. [PubMed<\/a>]<\/span><\/div>\n<\/div>\n<\/div>\n
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10.<\/div>\n
Kim W, Liebetrau C, Renker M, Rolf A, Van L, Arsalan M, Husser O, M\u00f6llmann H, Hamm C, Walther T. Transfemoral aortic valve implantation using a self-expanding transcatheter heart valve without pre-dilation. Int J Cardiol<\/i> 2017;243<\/b>:156\u2013160. [PubMed<\/a>]<\/span><\/div>\n<\/div>\n<\/div>\n
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11.<\/div>\n
Kim W, Blumenstein J, Liebetrau C, Rolf A, Gaede L, Van L, Arsalan M, Doss M, Tijssen J, Hamm C, Walther T, M\u00f6llmann H. Comparison of outcomes using balloon-expandable versus self-expanding transcatheter prostheses according to the extent of aortic valve calcification. Clin Res Cardiol<\/i> 2017;106<\/b>:995\u20131004. [PubMed<\/a>]<\/span><\/div>\n<\/div>\n<\/div>\n
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12.<\/div>\n
Husser O, Kim W, Pellegrini C, Holzamer A, Walther T, Mayr P, Joner M, Kasel A, Trenkwalder T, Michel J, Rheude T, Kastrati A, Schunkert H, Burgdorf C, Hilker M, M\u00f6llmann H, Hengstenberg C. Multicenter Comparison of Novel Self-Expanding Versus Balloon-Expandable Transcatheter Heart\u00a0Valves. JACC Cardiovasc Interv<\/i> 2017;10<\/b>:2078\u20132087. [PubMed<\/a>]<\/span><\/div>\n<\/div>\n<\/div>\n
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13.<\/div>\n
Kim W, Gaede L, Husser O, Liebetrau C, Renker M, Rolf A, Fischer-Rasokat U, M\u00f6llmann S, Blumenstein J, Guenther E, Van L, Arsalan M, Doss M, Loders S, Arnold M, Hamm C, Walther T, Achenbach S, M\u00f6llmann H. Computed Tomography for Diagnosis and\u00a0Classification of Bicuspid Aortic Valve\u00a0Disease in Transcatheter Aortic Valve Replacement. JACC Cardiovasc Imaging<\/i> 2018; [PubMed<\/a>]<\/span><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n\n
Twittern<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"

Die Arbeitsgruppe strukturelle\u00a0 Kardiologie besch\u00e4ftigt sich mit der interventionellen Therapie struktureller Herzerkrankungen. Klinisch werden in diesem Zusammenhang alle M\u00f6glichkeiten der interventionellen Klappentherapie inkl. z.b. Transkatheter-Aortenklappenimplantationen, […] Read More<\/a><\/span><\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"yoast_head":"\nArbeitsgruppe Strukturelle Kardiologie | KHFI<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.khfi.de\/khfiweb\/?page_id=1507\" \/>\n<meta property=\"og:locale\" content=\"de_DE\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Arbeitsgruppe Strukturelle Kardiologie | KHFI\" \/>\n<meta property=\"og:description\" content=\"Die Arbeitsgruppe strukturelle\u00a0 Kardiologie besch\u00e4ftigt sich mit der interventionellen Therapie struktureller Herzerkrankungen. 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